PT-141

PT-141 (Bremelanotide) is a melanocortin-receptor agonist studied in sexual-health research. It ships lyophilized and is reconstituted with bacteriostatic water before use.

Key research interest

PT-141 is studied across several research directions. The points below summarize what the published literature investigates — they describe research interest only, not outcomes, benefits, or any human-use claim.

• Studied for sexual-arousal and libido endpoints in clinical research
• Researched for centrally-mediated (non-vascular) mechanisms of action
• Investigated for melanocortin-receptor signaling in the CNS
• Examined for effects in both male and female research populations
• Studied as a metabolite-derived analog of Melanotan II without tanning focus

Mechanism of action

A melanocortin-receptor agonist (primarily MC4R) studied for acting on central nervous system pathways in the hypothalamus rather than the vascular system, distinguishing it from PDE5-inhibitor mechanisms in sexual-health research.

PT-141 research reference

Reference figures summarized from published research literature for context only. These are not instructions, protocols, or dosing advice — PT-141 is a research compound for laboratory use, not for human consumption.

• Published research range: Published research uses low mg-range single doses (research range)
• Administration (in research): Subcutaneous
• Storage & handling: Refrigerate after reconstitution; used within 30 days in most research protocols.

Get it & verify it

PT-141 sits at the center of a small content cluster on this site. Whether you are sourcing a vial, preparing one, or checking a Certificate of Analysis, start with the relevant guide below.

• Where to buy PT-141 — the 2026 buying guide: what to verify and how the tested vendors compared.
• PT-141 reconstitution calculator — compute concentration per insulin-syringe unit from your vial and BAC water.
• PT-141 COA guide — how to read a PT-141 Certificate of Analysis line by line.

Sourcing PT-141 in 2026

The 2025–2026 vendor shakeout put the burden of verification on the buyer. Treat every PT-141 listing as unproven until it ships with a batch-specific Certificate of Analysis showing HPLC purity at or above 98% from a named third-party lab. In our 2026 blinded HPLC evaluation, ROEHN Research scored highest at 9.6/10 and was the only supplier where every tested sample met or exceeded its label claim — publishing a batch COA and shipping cold-chain by default. Peptide Research Review readers get 15% off a first order with code FREE15.

View PT-141 at ROEHN Research (code FREE15)→

Other other research compounds compounds

Melanotan II

PT-141 and all compounds referenced are for laboratory research use only — not for human consumption. Reference ranges are summarized from published research literature and are not medical, dosing, or therapeutic advice.