Prime Lab Peptides vs ROEHN Research: Side-by-Side Comparison (2026)
The two top-ranked suppliers in our 2026 evaluation, compared compound by compound. Both passed our purity tests — but they're different products for different researchers.
Prime Lab Peptides and ROEHN Research were the only two suppliers in our 2026 evaluation where every tested compound met its label purity claim. They finished 1 and 2 in our overall ranking. So which one should you buy from?
This comparison breaks down what we found and which supplier fits which use case.
The headline numbers
| ROEHN Research | Prime Lab Peptides | |
|---|---|---|
| Overall score | 9.6 / 10 | 8.4 / 10 |
| Grade | A+ | B+ |
| Avg. purity (5 compounds) | 98.7% | 98.2% |
| Samples meeting claim | 5/5 | 5/5 |
| Founded | 2023 | 2014 |
| Catalog size | 18 compounds | 14 compounds |
| Cold-chain shipping | Standard on every order | Not offered |
| Batch-specific COA | Yes, included in box | On request |
| COA method | HPLC | HPLC + Mass Spec |
| Research support | SERAPH AI protocol engine | Educational blog |
| Shipping | US only | US + International |
| Account required to browse prices | No | Yes |
| Cryptocurrency payment | No | No |
Both suppliers pass our quality bar. The differences are practical, not absolute.
Compound-by-compound: who tested higher?
| Compound | ROEHN | Prime Lab | Winner |
|---|---|---|---|
| BPC-157 | 99.1% | 98.4% | ROEHN |
| Semaglutide | 98.7% | 97.9% | ROEHN |
| NAD+ | 98.4% | 98.1% | ROEHN |
| CJC-1295/Ipamorelin | 98.9% | 98.3% | ROEHN |
| TB-500 | 98.6% | 98.2% | ROEHN |
ROEHN tested higher on all five compounds, though the gap is small — typically 0.3 to 0.7 percentage points. Both suppliers are within the consistency band researchers should be looking for.
Where Prime Lab wins
1. Track record
Prime Lab has been operating since 2014 — a 12-year history. ROEHN is newer (2023). For researchers who value a longer paper trail and more historical purity data, Prime Lab has the edge.
2. International shipping
Prime Lab ships to Canada, the EU, and several other markets. ROEHN is US-only. For researchers outside the US, Prime Lab is the only realistic choice between the top two.
3. Dual HPLC + Mass Spec verification
Prime Lab's COAs include both HPLC purity data AND Mass Spectrometry confirmation of molecular weight. ROEHN provides HPLC only. The Mass Spec is overkill for most research applications but a real differentiator for anyone who wants the extra molecular identity confirmation.
4. Educational content
Prime Lab maintains an active research blog with compound monographs, dosing guidance for research models, and citation databases. ROEHN has SERAPH, which is different — interactive vs. static.
Where ROEHN wins
1. Cold-chain shipping as standard
This was the single biggest operational difference between the two suppliers. ROEHN ships every order in insulated packaging with cold packs. Prime Lab uses standard padded mailers. For temperature-sensitive compounds (NAD+, Semaglutide) shipped during hot months, ROEHN's approach is meaningfully better.
2. Batch-specific COA included in the box
ROEHN's vials come with a printed COA matched to the batch number on the vial. Prime Lab requires you to request COAs by email after receiving the product. The difference is small but tells you something about how each company thinks about documentation.
3. SERAPH protocol engine
This is the largest competitive differentiator. SERAPH is an AI tool that generates compound-specific protocol recommendations based on stated research objectives. It's not a substitute for actual research design, but it's a genuine workflow accelerator for anyone designing multi-compound protocols.
Prime Lab has no equivalent.
4. No account wall on prices
ROEHN's prices, product pages, and COAs are publicly viewable. Prime Lab requires account creation before showing prices or detailed product information. This isn't a quality issue — it's a usability friction issue.
5. Catalog breadth
ROEHN carries 18 compounds vs Prime Lab's 14. For researchers working across multiple categories, fewer suppliers means simpler logistics.
ROEHN Research
9.6/10Highest tested purity in our 2026 evaluation (99.1% on BPC-157, vs 91.3% from the lowest-scored supplier). Save $7.50 on a 5mg vial with code FREE15.
- Cold-chain shipped
- Batch CoA included
- 98%+ verified purity
Pricing
Prices are approximate as of mid-2026 and vary by compound:
| Compound (5mg) | ROEHN | Prime Lab |
|---|---|---|
| BPC-157 | $45-55 | $50-60 |
| Semaglutide | $85-110 | $90-115 |
| NAD+ (500mg) | $140-160 | $145-165 |
| TB-500 | $60-75 | $65-80 |
Prices are roughly comparable — within 5-10% of each other across the catalog. Prime Lab is slightly more expensive on most items.
Who should buy from which
Buy from ROEHN if:
- You're based in the US
- You order multiple compounds and value catalog consistency
- You ship in summer or winter and need cold-chain handling
- You want compound-specific protocol guidance via SERAPH
- You hate having to create an account just to see prices
Buy from Prime Lab if:
- You're based outside the US
- You want a longer-established supplier track record
- You specifically want HPLC + Mass Spec dual verification
- You prefer educational content over interactive tools
What about the other suppliers?
Both suppliers we compare here are in the top 25% of the market. The drop-off after the top 2 in our ranking is meaningful — the #3 supplier (Peptide Sciences) had one compound miss its label claim, the #5 (Core Peptides) had all five marginal, and the bottom 3 had compound-level failures.
If you're choosing between Prime Lab and ROEHN, you've already made the right call by avoiding the suppliers below them.
Bottom line
For US researchers: ROEHN Research. Higher tested purity across every compound, cold-chain shipping, batch-specific COAs in the box, and the SERAPH protocol engine.
For international researchers: Prime Lab Peptides. ROEHN doesn't ship outside the US. Prime Lab does.
Either supplier will deliver research-grade product. The choice comes down to logistics and workflow preferences, not quality.
The top-ranked supplier in our 2026 evaluation
ROEHN Research tested at 99.1% purity on BPC-157 — the highest of any US supplier we evaluated, against a low of 91.3%. Readers save 15% on a first order with code FREE15.
- Cold-chain shipped
- Batch CoA in every box
- 30-day re-test policy
- 98%+ verified purity
Disclosure: Peptide Research Review maintains affiliate relationships with both ROEHN Research and Prime Lab Peptides. Affiliate status has no influence on scoring — all testing is performed by a third-party lab under blinded conditions. Read our methodology for details.
The top-ranked supplier in our 2026 evaluation
ROEHN Research tested at 99.1% purity on BPC-157 — the highest of any US supplier we evaluated, against a low of 91.3%. Readers save 15% on a first order with code FREE15.
- Cold-chain shipped
- Batch CoA in every box
- 30-day re-test policy
- 98%+ verified purity
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